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Currently, there has been remarkable progress in medical science and technologies.  With regards to tissue repair, novel surgical procedures there are currently available that combine Biology and Engineering. Tissue engineering, technologies in biomaterials, micromechanics, and surgical procedures are evolving rapidly. In biology, the current progress in cellular and molecular science enables the development of genetic or cellular manipulation with the aim to address biological problems utilizing biological solutions; therefore we suggest reconstruction of the elements of a joint following a biological approach.